I.U.B.: 3.4.21.50

C.A.S.:  72561-05-8

Enzymatic Reaction Preferential cleavage: Lys, including -LysPro-

Endoproteinase-Lys-C  is a serine endoproteinase that specifically cleaves peptide bonds at the carboxyl side of lysine. It has a molecular weight of 30,000 daltons and is used in optimal pH range of 7.0-9.0. Lys-C is inhibited by diisopropylfluorophosphate, TLCK, Aprotinin and Leupeptin. 

Characteristics of Endoproteinse Lys-C:

Molecular weight:

30kda (Achour, 2013)

Optimum pH:

8.0

Inhibitors:

Diisopropyl fluorophosphate (DFP), TLCK, Aprotinin, Leupeptin