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What are the basic differences among the four types of collagenase?
| CLS-1 | Contains average amounts of assayed activities (collagenase, caseinase, tryptic and clostripain). Recommended for epithelial, liver (hepatocytes), lung, fat (adipocytes) and adrenal cell isolations. |
| CLS-2 | Contains greater proteolytic activities, especially clostripain activities. It is generally used for heart (cardiomyocytes), bone, muscle, thyroid, cartilage and endothelial cells. |
| CLS-3 | All activities lower than average. Low caseinase and low proteolytic activity. It is usually used for mammary cells and other soft tissues. |
| CLS-4 | Selected because of low tryptic activity. High collagenase required. It is commonly used for pancreatic islets and other applications where receptor integrity is crucial. |
